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HOME > J Korean Soc Clin Toxicol > Volume 4(2); 2006 > Article
Neurotoxic Shellfish Poisoning after Ingesting Whelk
Young-Gil Ko, Ji-Young Ahn, Seok-Yong Ryu, Sang-Lae Lee, Suk-Jin Cho, Mi-Ran Kim
Journal of The Korean Society of Clinical Toxicology 2006;4(2):147-150
DOI: https://doi.org/
Published online: December 31, 2006
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1Departments of Emergency Medicine, Inje University Seoul Paik Hospital
2Departments of Emergency Medicine, Inje University Seoul Paik Hospital
3Departments of Emergency Medicine, Inje University Sang-Gae Paik Hospital
4Departments of Emergency Medicine, Inje University Sang-Gae Paik Hospital
5Departments of Emergency Medicine, Inje University Sang-Gae Paik Hospital
6Departments of Emergency Medicine, Inje University Pusan Paik Hospital

Neurotoxic shellfish poisoning (NSP) can result from eating filter-feeding shellfish carrying brevetoxins produced by the marine dinoflagellate Krenia brevis (formally Gymnodinium breve). Brevetoxins enhance sodium entry into cells via voltage-sensitive sodium channels and have an excitatory effect. The incubation period is three hours (range 15 minutes-18 hours). NSP is characterized by gastroenteritis combined with neurologic symptoms. Gastrointestinal (GI) symptoms include abdominal pain, nausea, diarrhea and burning pain in the rectum. Neurologic symptoms are paresthesia, reversal of hot and cold temperature sensation, myalgia, headache, vertigo, and ataxia. Other symptoms may include malaise, tremor, dysphagia, bradycardia, decreased reflexes, dilated pupils, seizure, and coma. The health problem caused by K. breviscan be associated with a red tide bloom. We encountered 3 cases of neurotoxic shellfish poisoning. They all presented with GI and neurologic symptoms andrecovered after conservative treatment.

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JKSCT : Journal of The Korean Society of Clinical Toxicology