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- A Case of Prolonged Coagulopathy in a Patient Intoxicated with Superwarfarin Rodenticide
- Chan-Woo Park, Jun-Hwi Cho, Joon-Ho Bae, Joong-Bum Moon, Sung-Bin Chon, Ki-Ohk Ahn, Hui-Young Lee
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Journal of The Korean Society of Clinical Toxicology 2011;9(2):113-116
DOI: https://doi.org/
Published online: December 31, 2011
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1Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University
2Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University
3Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University
4Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University
5Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University
6Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University
7Department of Internal Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University
2Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University
3Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University
4Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University
5Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University
6Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University
7Department of Internal Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University
Abstract
Superwarfarin, such as brodifacoum, is a highly lethal vitamin K antagonist used as a rodenticide. Brodifacoum has a particularly long half-life in the body, which ranges to several months, and therefore requires prolonged treatment with antidotal vitamin K. We experienced a case whereby an 18-year-old male was presented to the hospital with a severe bleeding disorder. It was discovered that he had ingested brodifacoum rodenticide with intent to commit suicide. Despite continual treatment with vitamin K, the bleeding disorder persisted for several months before he recovered. We report this case with literature review.
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Korean Society of Clinical Toxicology