- A Case of Colchicine Intoxication Presenting as Acute Gastroenteritis
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Ji-Yun Ahn, You-Dong Sohn, Hyuk-Sool Kwon, Hee-Chol Ahn
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J Korean Soc Clin Toxicol. 2008;6(2):138-141. Published online December 31, 2008
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 Abstract
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- A 47-year-old woman ingested about 12 mg of colchicine with suicidal intent. Colchicine, a highly poisonous alkaloid, is a commonly used treatment for gout, Bechet's disease, and familial Mediterranean fever. Despite the knowledge of its side effects, the risk of a significant overdose is under-appreciated. She suffered from acute multisystem toxicity, including gastrointestinal disorders, bone marrow suppression, alopecia, and probable pancreatitis, but she ultimately recovered with supportive therapy. We report a case of acute colchicine toxicity from a single overdose with a review of the literature.
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KSCT
Korean Society of Clinical Toxicology